Blog Post Author: Reza Ghasemi
As per a research paper by Ortega et al. published in Nature Communications on Aug 6th 2021(cited below):
Q: If I experienced symptomatic COVID, although I’m vaccinated against it, what happens to my pre-existing SARS-CoV-2 antibodies during that time?
A:
▪︎Both quantity and quality of your SARS-CoV-2 antibodies changes when time passes.
▪︎When we are vaccinated or infected with COVID-19, the main antibodies produced in our body are IgM and IgG, which are mostly indicative of early and late response to the infection, respectively.
▪︎ Various antibodies are produced against different parts of the virus, thus, several types of IgG and IgM are identifiable.
▪︎A recent paper proved that the level of IgM and IgG in response to some parts of the virus changed over the time. The main clinical role of antibodies (e.g. neutralizing capacity), increased in early stages, then stood on a maximum level.
▪︎Probably the most interesting result extracted from this research is that your pre-existing antibodies for the common cold have a protective effect on COVID.
▪︎You may ask why the researchers decided to evaluate this antibody? Well! The answer is, the virus responsible for the human common cold is a member of human coronavirus family.
Information Sourced From: Ortega, N., Ribes, M., Vidal, M., Rubio, R., Aguilar, R., Williams, S., . . . Dobaño, C. (2021). Seven-month kinetics of Sars-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses. Nature Communications, 12(1). doi:10.1038/s41467-021-24979-9
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