Cancer is the deadliest human disease and the development of new diagnosis methods is important to increase the chances of a cure.
In this work, a new method was developed, named here for the first time as cerumenogram, that uses cerumen (earwax) as a new biomatrix for diagnosis.
Earwax samples collected from cancer patients (cancer group) and cancer-free patients (control group) were analyzed by Headspace/Gas Chromatography-Mass Spectrometry (HS/GC-MS), followed by multivariate analysis steps to process the raw data generated.
In total, 158 volatile organic metabolites (VOMs) were identified in the cerumen samples.
The 27 selected as potential VOMs biomarkers for cancer provided 100% discrimination between cancer and control groups.
This new test can thus be routinely employed for cancer diagnoses that are non-invasive, fast, cheap, and highly accurate.
Published: 13 August 2019
source:
https://www.nature.com/articles/s41598-019-48121-4
https://doi.org/10.1038/s41598-019-48121-4
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